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[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Antolini M, Debetto P, Trevisi L, Luciani S

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Dihexa was designed specifically to survive first-pass metabolism better than parent angiotensin IV analogs, but most vendor oral capsule claims are not supported by peer-reviewed pharmacokinetic data in humans

With an increase in calcium oxalate concentration, the expression of p53, ACSL4 and TRC in renal tubular epithelial cells increased, while the expression of SLC7A11 and GPX4 decreased significantly, indicating the centrality of ferroptosis in CaOx crystal-induced renal injury [171]