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Methods 325 , 108349 (2019)
In clinical trials involving over 2,000 patients across various conditions, no clinically significant adverse reactions were attributed to thymosin alpha-1 administration
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Athira Pharma (formerly M3 Biotechnology), the WSU spinout founded to commercialize Dihexa-derivative compounds, paid approximately $4 million in a False Claims Act settlement in January 2025 after a whistleblower exposed concealment of the research misconduct from federal grant agencies, and approximately $10 million in a separate class-action settlement to investors
Previous reports also suggest downregulation of ERK in GNE deficient cells 8,15,48
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