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According to KFF, in November 2025 at least 12% of adults in the United States were on a GLP-1 for one or multiple indications and more than half of patients report affordability challenges

Verdict: Limited evidence the absence of human trials reflects a combination of a cancelled unpublished safety study, specific FDA-documented safety concerns, and structural barriers that make large-scale human trials difficult to initiate and fund [4][10][1415]

The majority of individuals using Ozempic may encounter certain gastrointestinal side effects

Toxocariasis is an illness of humans caused by the dog roundworm (Toxocara canis) and, less frequently, the cat roundworm (Toxocara cati)

In clinical trials , people taking Wegovy lost an average of 15% of their body weight over a year, significantly more than people taking a placebo