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doi: 10.3390/ijms21113847, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 44

Physiol Res 2004

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Metformins brief plasma half-life of 26 h results in a steady-state metformin plasma concentration of approximately 415 M (0.52.0 g/mL) in individuals with T2D (Graham et al., 2011)