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Solving the crystal structures of MTAN co-crystallized with several inhibitors provided significant information about inhibitor-target interactions, and this is an essential step in exploring the potential of using the transition-state enzyme analogues as antibacterial drugs

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Microbiota-derived acetate enables the metabolic fitness of the brain innate immune system during health and disease

[3] [4] This metabolic involvement has led some to speculate about a connection between B12 and energy or fat metabolism a claim that warrants careful scrutiny