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A 2014 report from the surgeon general examining the past 50 years of smoking found that just a few cigarettes a day increases your risk of heart disease

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According to the American Lung Association, smoking-related illnesses are the single biggest preventable cause of death among African-Americans, killing about 45,000 a year

Therefore, the analysis of the leave-one-out plot reveals the potential positive impact of smoking on the risk of viral hepatitis and validates the robustness of our model and the rational use of SNPs as effective instrumental variables

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