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The study, published online December 9, 2019 in the American Journal of Respiratory and Critical Care Medicine, was co-authored by David Christiani, Elkan Blout Professor of Environmental Genetics, and Mi-Sun Lee, research associate in the Department of Environmental Health

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"The metal particles likely come from the cartridge of the e-cigarette devices themselves which opens up the possibility that better manufacturing standards for the devices could reduce the quantity of metals in the smoke," said Arian Saffari, a PhD student at USC Viterbi and lead author of the paper

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They have been largely unregulated for the past decade