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Lastly, islets of patients with T1D show preferential HLA-B hyper-expression when compared with non-diabetic donors, and islet-infiltrating CD8 + T cells reactive to HLA-B-restricted granule peptides are found in T1D donors

Proteins are the big machines doing heavy lifting Peptides are the tiny command buttons signaling to those machines when and how to work If proteins are hardware, Peptides are the software instructions

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Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters

DPP-4 inhibitors ("gliptins") prolong the action of native incretins