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Additionally, for various pathological conditions, including neurodegeneration, lysosomal and autophagy dysfunction occur concomitantly and both contribute to the disease progression [38,39], further supporting the close connection between lysosomal dysfunction and autophagy inhibition

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Extractions of an identical reaction with 1-hexanol were performed in parallel to assess the possible presence of glutathione transferase activity which could also transform the substrate 31

Hybrid structure of the RagA/C-Ragulator mTORC1 activation complex