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In those with positive findings or symptoms of distension and nausea, consider additional delay, prolonged fasting, or gastric decompression as appropriate

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GLP-1 regulates appetite and blood sugar by slowing gastric emptying so food stays in your stomach longer, signaling your brain to reduce hunger, improving insulin sensitivity, and reducing glucagon, which raises blood sugar

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Taking ibuprofen while on metformin can increase the risk of kidney problems and a rare but serious condition called lactic acidosis