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It belongs to a class of drugs called GLP-1 receptor agonists, which work by mimicking hormones that regulate blood sugar and appetite

Natural supplements operate under minimal FDA oversight and lack standardized potency testing, creating risks of contamination, mislabeling, or drug interactions

A review found that berberine has shown success in reducing fasting blood sugar levels and A1C

The identification and detection of biomarkers associated with ferroptosis activity are crucial for understanding its mechanisms in CAD and evaluating the efficacy of clinical interventions (56)

Therefore, additional, high-quality research would be needed to allow definite conclusions to be reached. Further complicating any assessments of the effects of berberine is the lack of uniformity in the amounts and formulations of berberine used in different studies, as well as the study participants themselves many of whom already had health conditions such as diabetes or fatty liver disease, which might have influenced the results