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305 The probiotic Lactobacillus reuteri (Lr) within melanoma promotes the local generation of IFN by CD8 + T cells through the release of its tryptophan breakdown metabolite, indole-3-aldehyde (I3A), thus enhancing ICI efficacy

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Keep in the original packaging: If researchers change the container, subjects may be more susceptible to infection due to increased risk of contamination

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Among these, random mutagenesis techniques such as ultraviolet (UV) irradiation effectively generate phenotypic diversity without using recombinant DNA technology (Jeyachandran et al., 2024)