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In contrast, immunomodulators have modest effects on HBsAg and have limited roles in monotherapy

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What To Expect During the Transition During the first 24 weeks after the switch, individuals may experience temporary changes, including: Mild nausea Fluctuating appetite Altered digestion or fullness cues Slower or faster weight changes These effects generally settle as the body adapts to tirzepatides dual-hormone activity

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Federal officials recently announced plans to make these medications more accessible and affordable, including to people who have Medicare, which currently does not cover medications strictly for weight loss