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In December 2025, federal courts consolidated NAION lawsuits into an MDL proceeding in the Eastern District of Pennsylvania

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Subsequently, the supernatant was removed, and 2.5 mL of media containing Cy5.5@vesicles (at a final concentration of 20 g/mL) was added to the cells, which were then incubated for 4 h at 37 C

Some users experience allodynia (heightened skin sensitivity) as a systemic side effect of semaglutide that manifests most noticeably at injection areas