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The overall incidence of serious adverse events was low, and researchers did not detect evidence of serious harm from nicotine e-cigarettes, though the longest follow-up was two years, and the number of studies was small

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Using the strictest and most rigorous methods, the CTAG reviews represent the gold standard in medical evidence, which is why CTAGs work is consistently used to inform guidelines and policies around the world, Jonathan Livingstone-Banks, PhD, a Lecturer and Senior researcher in evidence-based healthcare at the University of Oxford, and first author of the review, told Healthline