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If you have cardiovascular disease or significant risk, consult your clinician before beginning long-term use because of the unresolved TMAO issue

demonstrating that tesamorelin reduced visceral adipose tissue by a mean of 18% over 26 weeks compared to placebo in patients with abdominal fat accumulation remains the foundational reference for the drug

Very few absolute contraindications exist, but caution warranted for: severe peripheral vascular disease (circulation problems may worsen with compression), active scrotal infection (supportive underwear can trap moisture), acute testicular torsion (requires immediate surgery, not support), or severe skin sensitivity conditions

Always confirm with your prescribing provider if you're unsure about your specific timing

When a drug category is excluded from the plan's covered benefits, it means the employer or plan chose not to include it that is not a medical-necessity determination that can be reversed through an appeal