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On the one hand, ATF4 can drive sorafenib resistance in HCC by inhibiting ferroptosis [81]

Accordingly, supplementing OEA to obese mice reverses this state of dorsal striatal dopamine deficit in a vagal-afferentdependent manner [104]

NICE guidelines (NG136, NG28) recommend individualised blood pressure targets, typically below 140/90 mmHg for most people with diabetes, or below 130/80 mmHg if you have kidney, eye, or cerebrovascular disease

This helps us gather information about your BMI, medical history, and weight loss goals

Conditions such as obesity and type 2 diabetes are major risk factors for MASH, prompting interest in treatments that can address multiple aspects of metabolic syndrome