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Implications for Overall Growth Hormone Regulation Increasing Growth Hormone (GH) levels in adults through replacement therapy with recombinant GH has demonstrated several beneficial effects, particularly in addressing adult GH deficiency

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Synthetic Ghrelin Ligands It would appear therefore that the short half-life of acyl-ghrelin, the ubiquitous expression of GHSR-1a and the often overlooked presence of a functional antagonist in desacyl-ghrelin, leads to an unpredictable relationship between the pharmacokinetics and pharmacodynamics of ghrelin