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The advantages of repaglinide (the most popular meglitinide) over SUs are the ability to produce less hypoglycemia and the potential use in patients with moderate impaired renal function

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When initiating semaglutide in patients already taking levothyroxine, clinicians may consider checking TSH levels 6-8 weeks after starting treatment, particularly for patients using oral semaglutide (Rybelsus) due to its documented effect on thyroxine exposure

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