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Urolithin A activates the PTEN induced kinase 1 (PINK1)/Parkin RBR E3 ubiquitin protein ligase (PRKN) pathway, which tags dysfunctional mitochondria for degradation, while also stimulating mitochondrial biogenesis via the sirtuin 1 (SIRT1)/peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) signalling axis (Reference Ryu, Mouchiroud and Andreux15)

Oxidative-stress Detoxification and Signalling in Cyanobacteria: the Crucial Glutathione Synthesis Pathway Supports the Production of Ergothioneine and Ophthalmate

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