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99 Until more robust trials confirm their safety specifically in patients with reduced LVEF, GLP-1 RAs should be used cautiously in this population

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By integrating insights from neural development and classical neurodegeneration, this work will inspire future translational research into bilirubin-based therapeutic strategies to prevent or modify the progression of PD

TB-500 also has anti-apoptotic effects (reducing cell death) and modulates immune cells to limit excessive inflammation and fibrosis