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Despite numerous challenges, the synergistic role of ferroptosis and immune cell death (ICD) has opened up new dimensions for tumor treatment, and its successful translation will depend on the close integration of in-depth exploration of mechanisms and technological innovation

Furthermore, targeting what impairs glutamine to promote its anti-tumor effects can ameliorate therapies, for example, enhancing the expression of glutamine transporters in CD8 + T cells to improve glutamine consumption by these cells in comparison to tumor cells, fostering antitumor immunity

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1 2 Biochemistry (5th ed.)