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The flys nervous system shares significant functional and structural similarities with mammals, making it an ideal model for studying the molecular pathways underlying AD pathology

Moreover, genomics not only aids in identifying potential drug targets but also offers insights into drug mechanisms and the variability in individual responses to treatments [260]

447 In ischemia-reperfusion injury, high-density lipoprotein (HDL) inhibits BID-mediated mitochondrial apoptosis activation by regulating the expression and phosphorylation of the anti-apoptotic factor BCL-XL