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PMID: 7561636 Tomas FM, Lemmey AB, Read LC, Ballard FJ

"The role of the insulin-like growth factor 1 (IGF-1) in skeletal muscle physiology." In Vivo, 21(1), 45-54

For instance, the induction of genome-wide alterations in gene expression related to glucose and lipid metabolism in adipose tissues, skeletal muscles, and hepatic tissues of GHSR / mice by desacyl-ghrelin serves as substantiation for the presence of an unidentified desacyl-ghrelin receptor (40)

This study indicates that IGF-1 can increase the expression of HIF-1 and that a simulated hypoxic environment is favorable for the regeneration of precursor cells in cartilage