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In the case of the Russian research, they started with extracts from the thymus (left) and pineal glands (right)

Proteomic analyses identified a significant downregulation of cytoplasmic phospholipase A2 (cPLA2), a pivotal enzyme in pro-inflammatory mediator production, and modulation of the PPAR- pathway

265 LaudatiG.MascoloL.GuidaN.SirabellaR.PizzorussoV.BruzznatiS.et al (2019)

Increasing the half-life of peptides is possible by preventing their degradation by blood proteases through blocking the C- and N-termini of peptides or forming cyclically shaped peptides [29]

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