A dysesthesia signal (abnormal sensory perception) was observed in roughly 21% of patients at the 12mg dose, which warrants ongoing monitoring and clinical attention during titration
So you may get many of the systemic effects anyway, just with needles and a bigger bill
Cardiovascular symptoms : Palpitations, irregular heartbeat, or sensation of your heart racing or skipping beats Chest pain or tightness Unexplained fainting or near-fainting episodes Shortness of breath or difficulty breathing Allergic reactions or unusual symptoms : Rash, itching, swelling of the face, lips, or throat Difficulty swallowing or breathing Visual changes or severe headaches New or worsening mood changes, including depression or thoughts of self-harm (while a causal link with GLP-1 receptor agonists is unconfirmed, seek help promptly for any mental health concerns) For emergency situations such as severe chest pain, severe breathlessness, or collapse, call 999 immediately
Current and Resolved Drug Shortages and Discontinuations Reported to FDA
A randomized, controlled, blinded human trial of GHK-Cu monotherapy, with a vehicle-only control (and a needling-plus-vehicle arm if a procedure is used), objective endpoints such as blinded global photography and target-area hair counts over at least several months, adequate statistical power, pre-registration, and independent replication
