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Other potential DILI biomarkers under investigation include high-mobility group protein B1 (HMGB-1), a nuclear protein released during necrosis, and the ratio of cleaved to full-length cytokeratin [72]

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Patients with a history of long-term NSAID use who have developed gastric irritation or mucosal damage that persists despite stopping the NSAIDs

Identification of SLC39A4, a gene involved in acrodermatitis enteropathica

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