The Science: Why Belly Fat Is Harder to Lose There are two types of fat in the midsection: Subcutaneous fat (soft belly fat under the skin): The kind you can pinch Stores energy but isnt as dangerous Responds to long-term lifestyle change May reduce with calorie deficit, strength training, and metabolic support Visceral fat (fat stored inside the abdomen, around your organs): inside the abdomen, around your organs): You cant grab it but it makes your waist look wider, bloated, or hard Its inflammatory, metabolically risky, and associated with high cortisol and insulin resistance Hormonally protected, meaning your body fights to keep it under stress Slower to lose and usually the last to go Your body stores visceral fat as a survival mechanism
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Rheumatoid arthritis A large multi-center study using the TriNetX database found that GLP-1 receptor agonist use was associated with lower risk of developing immune-mediated inflammatory diseases in patients with type 2 diabetes or obesity
J Clin Invest (2007) 117(5):121922
The research also found that people living with health inequities or those who live in underserved areas were least likely to continue treatment
