Statistical analysis All statistical analyses were carried out using GraphPad Prism (GraphPad Software)
Cell Mol Life Sci 2005
doi: 10.1038/s41575020-00360-x 13 SiesH
American Journal of Physiology Renal Physiology 317(6):F1450F1461 Pereira ADS, Miron VV, Castro MFV, Bottari NB, Assmann CE, Nauderer JN, Bissacotti BF, Mostardeiro VB, Stefanello N, Baldissarelli J, Palma TV, Morsch VMM, Schetinger MRC (2023) Neuromodulatory effect of the combination of metformin and vitamin D3 triggered by purinergic signaling in type 1 diabetes induced-rats
More studies on the effects of the secondary metabolites in modulating the signaling pathways using experimental cell and vivo animal models of immune-related disorders are required together with elaborate preclinical pharmacokinetics, pharmacodynamics, bioavailability, and toxicity studies