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Side Effects and Unknown Long-Term Risks Nausea, vomiting, muscle loss, and fatigue are common side effects

The FDA boxed warning and contraindications for semaglutide apply at any dose (FDA Wegovy label)

Effect on Cardiovascular Health: In addition to its beneficial effects on glucose control and weight management, semaglutide has shown promising results in improving cardiovascular health

And yet, so many of us are stuck there in that in-between space

According to a recent review in Pharmacological Research , GLP-1 drugs may reduce brain inflammation, improve communication between brain cells, and influence important neurotransmitters such as dopamine and serotonin (2 Trusted Source Psychotropic effects of GLP-1R agonists Go to source)