Increased enzyme activity correlates with neurodegenerative diseases like Alzheimers and Parkinsons
The two axes feed each other in a positive loop that drives protein synthesis, fat oxidation, and connective tissue remodeling beyond what either hormone system achieves independently
In addition, most proposed therapeutic strategies are still at the stage of early basic research, and systematic evaluations of their target specificity, toxicity, and clinical translational potential are lacking
Oral microbiota-driven immune modulation along the oral-gut axis: from local signals to systemic inflammation
Some of these meal replacement plans remove entire food groups for extended periods of time, which can cause micronutrient deficiencies in iron, B12, magnesium, and potassium