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doi:10.1023/a:1005374027693 33.Bachmann C

Male Sprague-Dawley rats (Taconic derived) weighing 390-450 g were maintained with free access to water and food (Harland Tekland F6 rodent diet, Madison, WI) except the night prior to surgery when food was removed

One retrospective study of intra-articular knee injections reported symptomatic improvement lasting over six months following a single injection in 7 of 12 patients, suggesting potential for sustained effects beyond active treatment periods

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However, some concerns have been raised: Short-Term Side Effects Common side effects may include nausea, diarrhoea, and stomach discomfort