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Those pregnant, breastfeeding, or undergoing cancer treatment should avoid it until more data becomes available

The answer depends on three main factors: temperature, duration, and exposure conditions

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28 In contrast, the BRONCUS study in which patients received a daily dose of 600 mg NAC showed no benefit in COPD, 29 whereas in the HIACE and PANTHEON studies in which the dose was 600 mg twice daily (BID), a decrease in the frequency of acute exacerbations was observed with NAC

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