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It is unknown whether RYBELSUS causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as human relevance of semaglutide-induced rodent thyroid C-cell tumors has not been determined RYBELSUS is contraindicated in patients with a personal or family history of MTC and in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

Researchers evaluated 0.5 mg, 1.0 mg, and higher doses, assessing glycemic efficacy measured by HbA1c reduction alongside safety parameters

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These can vary widely from person to person

Insufficient time on therapy : Weight loss with semaglutide typically occurs gradually