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Alprostadil erections can occur without sexual arousal too (since its a local drug), and there is a risk of priapism or significant penile pain/burning

Conclusion GLP-1 is more than just a weight-loss aid

Arch Gen Psychiatry 2003

Nevertheless, supplementation with 2 mg/d folic acid, 25 mg/d vitamin B6, and 400 g/d B12 during 6 months significantly decreased the homocysteine levels, severity, and disability of migraine attacks (60)