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For Ozempic and Wegovy: Unopened pens must be stored in the refrigerator at temperatures between 36F and 46F (2C to 8C) Keep in the original carton to protect from light exposure Never store in the freezer

In the same way, CAR-T cells therapy targeting uPAR protein displays a huge in vitro and in vivo senolityc activity and could be considered in a close future as an alternative solution to definitively eradicate senescent cells in rejuvenation or to treat age-related diseases

However, anaesthetists must be aware that withholding the therapy in patients with type 2 diabetes mellitus may increase the risk of perioperative hyperglycaemia, which can, in turn, elevate the likelihood of postoperative complications, such as wound infections [22]