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AOD-9604 is supplied as a lyophilised powder and is reconstituted prior to use with sterile bacteriostatic water

Downregulation of N-WASP or deletion of its Arp2/3 binding region in hippocampal neurons resulted in decreased spine and synapse density (Wegner et al., 2008)

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Circulating BDNF can be measured in serum, plasma or whole blood

It gets pushed as being a more natural form as it is an analogue of one of the forms used in the processes in your cell but reality is that the biochemistry of getting cobalamin from blood to cells makes this irrelevant