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Methods: An expert working group (EWG) comprising ten pulmonologists and a multidisciplinary drafting committee reviewed data from in vitro , mechanistic, animal and observational studies, randomized trials, reviews and meta-analyses for role of NAC in respiratory diseases

10.1038/nri2062 111 TanJ.XuX.TongZ.LinJ.YuQ.LinY.et al (2015)

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The Food and Drug Administration (FDA) sets the legal status of peptides based on the specific peptide and its intended use, so not all peptides are legal in the U.S

Therefore, there is no compelling research to suggest the use of citrulline malate over pure citrulline