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CONCLUSION Oxidative stress is a key contributor to numerous physiological and psychological disorders, with cortisol and glutamate playing pivotal roles in its pathology

Collectively, these findings indicate that reduced adipocyte mitochondrial CI activity during obesity is a key driver of visceral WAT metabolic dysfunction and subsequent systemic impairment in metabolic health

In clinical trials, participants using Semaglutide experienced significant weight loss

Metabolic health is a big factor

Aligned BAM files from the DRAGEN RNA pipeline were used for downstream differential expression analysis and data visualization