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10.1186/s13045-019-0720-y 17 NehraS.BhardwajV.BansalA.ChattopadhyayP.SaraswatD

Common side effectsnausea, vomiting, constipationmay be more pronounced in menopausal women due to altered GI motility from hormonal changes

Arsenic trioxide (As 2 O 3 ) is a prooxidant chemotherapeutic compound combined with agents that deplete cellular GSH [116]

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This selective approach may explain why hydrogen studies consistently show benefits without the potential downsides observed with high-dose traditional antioxidants, which sometimes show null or even negative effects in clinical trials