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doi: 10.2174/138920011796504536 : Mielgo-Ayuso J, Pietrantonio L, Viribay A, Calleja-Gonzlez J, Gonzlez-Bernal J, Fernndez-Lzaro D

Siczek K, Zatorski H, Chmielowiec-Korzeniowska A, Kordek R, Tymczyna L, Fichna J (2017) Evaluation of anti-inflammatory effect of silver-coated glass beads in mice with experimentally induced colitis as a new type of treatment in inflammatory bowel disease

NAION occurs due to reduced blood flow to the front portion of the optic nerve without inflammation of the blood vessels, and typically causes sudden, painless vision loss in one eye

However, chelating agents like EDTA should be avoided in GHK-Cu formulations, as they competitively bind copper and destabilize the peptide-metal complex, resulting in reduced biological activity

The prescribing information for these medications contains a boxed warning regarding the potential risk of thyroid C-cell tumors, a rare form of thyroid cancer