The findings suggest that weight loss can enhance the effectiveness of circulating estradiol (a potent form of oestrogen), as lower body fat reduces estrone production, which can counteract the beneficial effects of estradiol
Int J Mol Sci (2020) 21(9):3165
Gastro-intestinal symptoms score was assessed based on the score of Adam and collaborators 16 as follows: Parents were asked to indicate whether their children had experienced specific GI symptoms nausea, vomiting, bloating, abdominal cramps, early satiety, eructation or heartburn, loss of appetite, retrosternal discomfort and epigastric pain or abdominal pain over the past month
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In mouse and rat models of choline and methionine-deficient diet-induced metabolic dysfunction-associated steatotic liver disease (MASLD), females are reported to be more protected than their male counterparts 88