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Individuals who are low in B12 may experience persistent fatigue, weakness, or lightheadedness, along with difficulties concentrating or a sense of brain fog

There is a psychological component too

Hypermagnesemia Disturbances in Rats, NO-Related: Pentadecapeptide BPC 157 Abrogates, L-NAME and L-Arginine Worsen

This decline isn't cosmetic, it's mechanistically linked to mitochondrial dysfunction, compromised DNA repair capacity, and the cellular hallmarks of aging that researchers like David Sinclair and others have spent decades documenting

Some of these medications include: fluphenazine (Prolixin) magnesium salicylate (Novasal) mexiletine (Mexitil) salsalate There is some concern that high-dose vitamin C might make radiation therapy and some chemotherapy drugs less effective