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It is now widely used in research settings as a tool compound for studying GH-derived fragments and selective lipolytic signalling

The key changes include an amino acid substitution at position 8 (alanine to aminoisobutyric acid) that provides DPP-4 resistance, and a C-18 fatty diacid chain attached via a spacer to lysine at position 26 that lets albumin binding

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Nii and coworkers investigated the parameters influencing the drug deposition pattern after intranasal administration using an in-vitro 3D nasal model covered with Sar-Gel paste