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This is also evidenced by observations that changes in intestinal motility and the gut microbiota are key factors in IBS, along with inflammatory immune activation, all three factors that converge in a feedback loop [295]

Vitamin B12 and Its Importance in the Human Body Vitamin B12, also known as cobalamin, is a crucial water-soluble vitamin that plays a vital role in various bodily functions

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doi: 10.1038/s41467-021-21841-w 22 YuXLongYC

Last reviewed: May 2026 Medically reviewed by Mohammed Lakhi Superintendent Pharmacist