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Tomato-based or broth-based sauces, and those that include vegetables and lean ground beef, turkey, or chicken are often easier to tolerate

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Central to this concept linking neural and systemic functions is the concept of allostasis (adaptation) and allostatic load/overload (pathophysiology) [6] that emphasizes the role of endogenous mediators for adaptation in contributing to pathologies, including MDD, when activated persistently or dysregulated under circumstances of toxic stress and health-damaging behaviors (poor diet, excessive alcohol consumption, sleep deprivation and circadian disruption)

The important distinction is that saying methylfolate may be superior is not the same as saying folic acid does not work