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For each population, we specified seven target trials separately comparing semaglutide with insulin, metformin, dipeptidyl-peptidase-4 inhibitors (DPP-4i), sodium-glucose cotransporter-2 inhibitors (SGLT2i), sulfonylureas (SUs), thiazolidinediones (TZDs), and the first-generation GLP-1RAs (albiglutide, dulaglutide, exenatide, liraglutide, and lixisenatide)

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With proper reconstitution, you can accurately dose anywhere from 1mg to 12mg weekly, adjusting based on your response and tolerance