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Yamagishi, S

PMID: 34687865 Cell Rep Microglial macrophage-derived ds-HMGB1 in DRG orchestrates neuropathic pain through immune-neural signaling

This review highlights the biological activities of IGF-IR signaling in cancer and the contribution of IGF-IR to cytotoxic, endocrine, and molecular targeted therapies resistance

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The excessive release of proinflammatory cytokines (such as TNF-, IL-1, and IL-6) also leads to systemic coagulation abnormalities, collectively triggering a systemic inflammatory cascade, resulting in immune imbalance and aggravated lung injury