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To understand the significance of GLP-1 drugs, it is essential to appreciate the background of the incretin effect and the early quest for gut-derived diabetes treatments

We need to answer many questions before proceeding with recommendations, yet

Nevertheless, when kidney injuries are prolonged and overreacted, this reaction becomes pathogenic, ultimately contributing to the emergence of ESRD (Inker et al., 2014)

Ideally, well start you out with a small dosage of GLP-1, then gradually build your dosage up over time