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At present, the main treatment of prostate cancer is generally divided into four methods: surgery, chemotherapy, radiotherapy and endocrine therapy

This often results in more severe nausea, vomiting, or diarrhea

To prolong the function of the GLP-1 polypeptide, medicinal chemists have decorated this polypeptide molecule, by modifying some functional groups in the GLP-1 polypeptide molecular structure, and by adding a lipophilic 18-carbon fatty acid branch to the 26 th amino acid, leading to the ultimate design of semaglutide

Side-effect trends mirror this split MT-1 reactions stay skin-focused, whereas MT-2 extends into systemic responses

Nature Reviews Immunology , 9 (11), 799809